BDBM42279 (R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,3,5-triazin-2-yl)piperazin-1-yl)pyrimidin-5-yl)vinyl)pyridin-2-yl)oxazole::WO2024186584, Example 41

SMILES FCCOC[C@H]1CN(CCN1C1=NC=NC=N1)C1=NC=C(C=N1)/C=C/C=1C=CC(=NC1)C1=CN=CO1

InChI Key InChIKey=JGJMAGYJXPIPPW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42279   

TargetAlpha-synuclein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42279BDBM42279((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,...)
Affinity DataKi:  0.800nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42279BDBM42279((R,E)-5-(5-(2-(2-(3-((2-fluoroethoxy)methyl)-4-(1,...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent