BDBM42304 3-(((R)-4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)ethynyl)pyrimidin-2-yl)-1-(pyrimidin-2-yl)piperazin-2-yl)methoxy)-2-fluoropropan-1-ol::WO2024186584, Example 63

SMILES N1(C=NC=C1)C1=CC=C(C=N1)C#CC=1C=NC(=NC1)N1C[C@@H](N(CC1)C1=NC=CC=N1)COCC(CO)F

InChI Key InChIKey=FSKSVPYYRDWVDD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42304   

TargetAlpha-synuclein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42304BDBM42304(3-(((R)-4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)et...)
Affinity DataKi:  0.913nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42304BDBM42304(3-(((R)-4-(5-((6-(1H-imidazol-1-yl)pyridin-3-yl)et...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent