BDBM42307 1-(4-(6-fluoropyrimidin-4-yl)-1-(5-((6-(oxazol-5-yl)pyridin-3-yl)ethynyl)pyrimidin-2-yl)piperazin-2-yl)-N-methylmethanamine::WO2024186584, Example 65

SMILES FC1=CC(=NC=N1)N1CC(N(CC1)C1=NC=C(C=N1)C#CC=1C=NC(=CC1)C1=CN=CO1)CNC

InChI Key InChIKey=CXJQOMGZPJXBQP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 42307   

TargetAlpha-synuclein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42307BDBM42307(1-(4-(6-fluoropyrimidin-4-yl)-1-(5-((6-(oxazol-5-y...)
Affinity DataKi:  1.10nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent

TargetAmyloid-beta precursor protein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42307BDBM42307(1-(4-(6-fluoropyrimidin-4-yl)-1-(5-((6-(oxazol-5-y...)
Affinity DataKi:  1.20E+3nMAssay Description:Emory Chemistry-Biology Discovery Center Assay Overview: MLSCN Grant: 1 X01MH78953-01 Hsp90 is a chaperon with important roles in maintaining transfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent