BDBM42341 (R)-2-(4-(6-fluoropyrimidin-4-yl)-3-(methoxymethyl)piperazin-1-yl)-5-((2-(1-methyl-1H-pyrazol-4-yl)pyrimidin-5-yl)ethynyl)pyrimidine::WO2024186584, Example 94

SMILES FC1=CC(=NC=N1)N1[C@H](CN(CC1)C1=NC=C(C=N1)C#CC=1C=NC(=NC1)C=1C=NN(C1)C)COC

InChI Key InChIKey=JTDWUZNQNOVCKN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 42341   

TargetAlpha-synuclein(Human)
Galderma Research & Development

US Patent
LigandChemical structure of BindingDB Monomer ID 42341BDBM42341((R)-2-(4-(6-fluoropyrimidin-4-yl)-3-(methoxymethyl...)
Affinity DataKi:  0.760nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details
US Patent