BDBM426126 5-(8-Morpholino-2-phenyl-imidazo[1,2-a]pyrazin-3-yl)indolin-2-one;::US10513523, Example 65

SMILES O=C1Cc2cc(ccc2N1)-c1c(nc2c(nccn12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=UQDDKBKLMCJQHT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426126   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426126(US10513523, Example 65 | 5-(8-Morpholino-2-phenyl-...)
Affinity DataIC50: 0.160nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
US Patent