BDBM426213 5-(2-Benzoyl-8-morpholino-imidazo[1,2-a]pyrazin-3-yl)indolin-2-one;::US10513523, Example 153

SMILES O=C(c1nc2c(nccn2c1-c1ccc2NC(=O)Cc2c1)N1CCOCC1)c1ccccc1

InChI Key InChIKey=ZKKOBIRDZDDYCP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 426213   

TargetGlutamate receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM426213(US10513523, Example 153 | 5-(2-Benzoyl-8-morpholin...)
Affinity DataIC50: 0.320nMAssay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
10/24/2020
Entry Details
US Patent