BDBM426810 US10544110, Compound JJ-450B
SMILES Cc1ccc(Cl)cc1N1CCN(CC1)C(=O)[C@@H]1C[C@@H]1c1ccc(F)cc1
InChI Key InChIKey=ITRMZYSEZBCBEC-RTBURBONSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 426810
Affinity DataIC50: 1.31E+4nMAssay Description:The biological activity of analogs 5-16, 18, 20, 26, JJ-450, and the resolved enantiomers JJ-450A and J-450B was determined and compared to HTS hit 1...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Antagonist activity at Androgen receptor in human LNCaP C4-2 cells transfected with PSA6.1-luc and pRL-TK measured by luciferase gene reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.52E+4nMAssay Description:Antagonist activity at androgen receptor in human C4-2-PSA-rl cells incubated for 24 hrs in presence of androgen R1881 by dual-glo luciferase reporte...More data for this Ligand-Target Pair