BDBM427172 US10544132, Example 113::US11236047, Example 113

SMILES CC[C@@](O)(c1cc2C(=O)N([C@@H](CCC(O)=O)c3ccc(OC)cc3)[C@](OC)(c2c(F)c1)c1ccc(Cl)cc1)C1(F)CCOCC1

InChI Key InChIKey=NOKLTVPSPDXSBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 427172   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 427172BDBM427172(US10544132, Example 113 | US11236047, Example 113)
Affinity DataIC50: 6.90nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 ul per well of 1 μg ml−1 biotinylated IP3 pep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 427172BDBM427172(US10544132, Example 113 | US11236047, Example 113)
Affinity DataIC50: 5.70E+4nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent