BDBM427181 US10544132, Example 122

SMILES CC[C@](O)(C1CCOCC1)c1cc2C(=O)N(Cc3ccc(Cl)cc3CC([O-])=O)C(OC)(c2c(F)c1)c1ccc(Cl)cc1

InChI Key InChIKey=KSQHEVCOEVTEOI-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 427181   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Astex Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 427181BDBM427181(US10544132, Example 122)
Affinity DataIC50: 8.80E+4nMAssay Description:The ELISA assay was performed in streptavidin coated plates which were preincubated with 200 μl per well of 1 μg ml−1 biotinylated IP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details
US Patent