BDBM432102 US10577330, Comparison Compound C11
SMILES Cc1cc(Cl)cc([C@@H](CC(O)=O)NC(=O)CNC(=O)c2cccc(NC3=NCCN3)c2)c1O
InChI Key InChIKey=DRRGYLNTFDGRHO-QGZVFWFLSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 432102
Affinity DataIC50: 33nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Recombinant mouse nephronectin protein (R&D Systems, Inc, 4298-NP) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Recombinant human LAP protein (R&D Systems, Inc, 246-LP) diluted to 0.5 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, ...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) at 0.25 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Recombinant human LAP (R&D Systems, 246-LP) diluted to 0.25 g/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 mM MgCl2, ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2,...More data for this Ligand-Target Pair