BDBM4326 2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedinitrile::benzylidenemalononitrile (BMN) deriv. 10

SMILES [#8]-c1cc(\[#6]=[#6](/C#N)C#N)ccc1-[#7+](-[#8-])=O

InChI Key InChIKey=DUQADSPERJRQBW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4326   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

LigandPNGBDBM4326(2-[(3-hydroxy-4-nitrophenyl)methylidene]propanedin...)
Affinity DataKi:  1.50E+5nM ΔG°:  -5.16kcal/mole IC50:  4.50E+5nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
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