BDBM433029 5-cyclopropyl-N-((2S,4R,5S)-2,5- dimethyl-1-((2-(pyrrolidin-1- yl)ethyl)sulfonyl)piperidin-4-yl)isoxazole- 3-carboxamide::US10577363, Compound 732

SMILES C[C@H]1CN([C@@H](C)C[C@H]1NC(=O)c1cc(on1)C1CC1)S(=O)(=O)CCN1CCCC1

InChI Key InChIKey=VDMGPWHSTYXFKT-YQQAZPJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433029   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM433029(5-cyclopropyl-N-((2S,4R,5S)-2,5- dimethyl-1-((2-(p...)
Affinity DataIC50:  431nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent