BDBM434223 US10562891, Example 145::US11008308, Example 145

SMILES Cc1cccc(CN2CCC(CC2)SCc2nc3c(C)cccc3c(=O)[nH]2)n1

InChI Key InChIKey=XLMXRYFHECMHGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 434223   

TargetProtein mono-ADP-ribosyltransferase PARP14 [1611-1801](Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434223(US10562891, Example 145 | US11008308, Example 145)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent

TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM434223(US10562891, Example 145 | US11008308, Example 145)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzymatic inhibition of PARP14 was measured using a dissociation-enhanced lanthanide fluorescence immunoassay (DELFIA) monitoring the auto-modificati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2021
Entry Details
US Patent