BDBM435429 US10570116, Compound C37

SMILES Cc1cccc2c(=O)[nH]c(CC(C)(C)CC(=O)N3CCC(C(=O)c4cccc(C(=O)O)c4)CC3)nc12

InChI Key InChIKey=ANMLHQJBUZSTOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435429   

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435429BDBM435429(US10570116, Compound C37)
Affinity DataIC50: 0.950nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435429BDBM435429(US10570116, Compound C37)
Affinity DataIC50: 2nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 435429BDBM435429(US10570116, Compound C37)
Affinity DataIC50: 1.50E+3nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent