BDBM435435 US10570116, Compound C43

SMILES COC(=O)c1cccc(c1)C(=O)C1CCN(CC1)C(=O)C[C@@H](C)Cc1nc2c(C)cccc2c(=O)[nH]1

InChI Key InChIKey=MOMSZDNLTDTPMD-KRWDZBQOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435435   

TargetPoly [ADP-ribose] polymerase 1(Human)
Merck Patent

US Patent
LigandPNGBDBM435435(US10570116, Compound C43)
Affinity DataIC50:  790nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF® (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Merck Patent

US Patent
LigandPNGBDBM435435(US10570116, Compound C43)
Affinity DataIC50:  0.630nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Merck Patent

US Patent
LigandPNGBDBM435435(US10570116, Compound C43)
Affinity DataIC50:  0.230nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent