BDBM435452 US10570118, Example 42::US10570118, Example 43::US10570118, Example 7

SMILES Cn1cc(cc1C(N)=O)-c1cccc(c1CO)-n1c(cc2cc(ccc2c1=O)C1CC1)C1CN(C1)C(=O)C=C

InChI Key InChIKey=DUCPRKRXLWAZPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435452   

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435452(US10570118, Example 42 | US10570118, Example 43 | ...)
Affinity DataIC50: 0.560nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435452(US10570118, Example 42 | US10570118, Example 43 | ...)
Affinity DataIC50: 0.700nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435452(US10570118, Example 42 | US10570118, Example 43 | ...)
Affinity DataIC50: 560nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent