BDBM435471 US10570118, Example 25

SMILES OCc1c(cccc1-n1c(cc2cc(ccc2c1=O)C1CC1)C1CCN(C1)C(=O)C=C)-c1ccn2cncc2c1

InChI Key InChIKey=SSSPQHSWSVUELO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435471   

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435471(US10570118, Example 25)
Affinity DataIC50: 160nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2020
Entry Details
US Patent