BDBM436179 US10590106, Compound C009

SMILES Fc1ccc(NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1Oc1ccc2ncc(nc2c1)N1CCOCC1

InChI Key InChIKey=CZTVJVLRTBEHFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 436179   

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM436179(US10590106, Compound C009)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′-LYTE Method as brief...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM436179(US10590106, Compound C009)
Affinity DataIC50: 100nMAssay Description:Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z'-LYTE Method as described above with the following m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2020
Entry Details
US Patent