BDBM436677 6-(3,4-Difluorophenyl)-3-methyl-1-[(5-methylisoxazol-3- yl)methyl]imidazo[4,5-b]pyridin-2-one::US10617676, Example 8::US11207298, Example 8

SMILES Cc1cc2c(F)c(Oc3ccnn4cc(C(=O)N5CCC(O)C5)c(C)c34)ccc2[nH]1

InChI Key InChIKey=OLFGRMRNTCSNFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436677   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436677BDBM436677((S or R)-{4-[(4-fluoro-2-methyl-1H- indol-5-yl)oxy...)
Affinity DataEC50:  1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent