BDBM436698 1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[2-methyl-5-(trifluoromethyl)phenyl]-3H- imidazo[4,5-b]pyridin-2-one::US10617676, Example 29::US11207298, Example 29

SMILES Cc1cc2cc(Oc3ccnn4cc(C(=O)N5CC(C#N)C5)c(C)c34)ccc2[nH]1

InChI Key InChIKey=XMJPUVYLGKKTNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436698   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436698BDBM436698(1-{5-methyl-4-[(2-methyl- 1H-indol-5- yl)oxy]pyrro...)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent