BDBM436715 6-(4-Fluoro-3-methyl-phenyl)-3-methyl-1-(4-pyridylmethyl)imidazo[4,5- b]pyridin-2-one::US10617676, Example 46::US11207298, Example 46

SMILES Cc1oc2cc(Oc3ccnn4cc(C(=O)N5CC(C#N)C5)c(C)c34)ccc2c1C(=O)NC1CC1

InChI Key InChIKey=RJNJTWPHYNXNOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436715   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436715BDBM436715(US20260022125, Example 14.1)
Affinity DataEC50:  0.490nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent