BDBM436728 6-(3,4-Difluorophenyl)-3-methyl-1-(3-pyridylmethyl)imidazo[4,5-b]pyridin-2- one::US10617676, Example 59::US11207298, Example 59

SMILES Cc1oc2cc(Oc3ccnn4cc(C(=O)N5CC(C#N)C5)c(C)c34)ccc2c1C(=O)NCC1CC1

InChI Key InChIKey=IRROWAIMLFNPIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436728   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436728BDBM436728(6-{[6-(3-cyanoazetidine-1- carbonyl)-5-methylpyrro...)
Affinity DataEC50:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent