BDBM436758 1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-6-[5-(hydroxymethyl)-2-thienyl]-3-methyl- imidazo[4,5-b]pyridin-2-one::US10617676, Example 89::US11207298, Example 89

SMILES Cc1oc2cc(Oc3ccnn4cc(C(=O)N5C[C@H](F)[C@H]5C)c(C)c34)ccc2c1C(=O)NC1COC1

InChI Key InChIKey=KEQOTBTUVWZKPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436758   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436758BDBM436758(6-({6-[(2R,3S)-3-fluoro-2- methylazetidine-1-carbo...)
Affinity DataEC50:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent