BDBM436786 6-[4-(Difluoromethyl)-2-thienyl]-1-[2-(3-fluoroazetidin-1-yl)-2-oxo-ethyl]-3- methyl-imidazo[4,5-b]pyridin-2-one::US10617676, Example 118::US11207298, Example 118

SMILES CNC(=O)n1c(C)cc2cc(Oc3ccnn4cc(C(=O)N5C[C@@H](O)[C@H]5C)c(C)c34)ccc21

InChI Key InChIKey=WGIDPSZCQIHBFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436786   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436786BDBM436786(US20260022125, Example 20.1)
Affinity DataEC50:  0.490nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent