BDBM436788 N,N-Dimethyl-2-[3-methyl-2-oxo-6-[5-(trideuteriomethoxymethyl)-2- thienyl]imidazo[4,5-b]pyridin-1-yl]acetamide::US10617676, Example 121::US11207298, Example 121

SMILES Cc1c(C(=O)N2C[C@H](F)[C@H]2C)cn2nccc(Oc3ccc4c(c3)cc(C)n4C(=O)N[C@H]3CC[C@@H]3O)c12

InChI Key InChIKey=LBXMYIYROVADBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436788   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436788BDBM436788(5-((6-((2R,3S)-3-fluoro- 2-methylazetidine-1- carb...)
Affinity DataEC50:  0.630nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent