BDBM436789 1-[2-(Azetidin-1-yl)-2-oxo-ethyl]-3-methyl-6-[5-(trideuteriomethoxymethyl)- 2-thienyl]imidazo[4,5-b]pyridin-2-one::US10617676, Example 122::US11207298, Example 122

SMILES Cc1c(C(=O)N2C[C@@H](O)[C@H]2C)cn2nccc(Oc3ccc4c(c3)cc(C)n4C(=O)NC3CC3)c12

InChI Key InChIKey=REDXBXXAHZIXIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436789   

TargetVascular endothelial growth factor receptor 2(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 436789BDBM436789(US20260022125, Example 21.1)
Affinity DataEC50:  0.350nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details US Patent