BDBM437160 US11802122, Example 57B

SMILES N#Cc3cc([C@@H](NC(=O)[C@@H]1CNC(=O)N1)c2ccc(OC(F)(F)F)cc2)ccc3Cl

InChI Key InChIKey=QEPBHTRFWCUOCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437160   

TargetSodium channel protein type 8 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 437160BDBM437160(US11802122, Example 57B)
Affinity DataIC50: 2.40nMAssay Description:The following buffers were used for the Qube recordings: External buffer for NaV1.8 Qube recording: 150 NaCl, 2 CaCl2, 5 KCl, 1 Mg Cl2, 10 HEPES, 12 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2023
Entry Details
US Patent