BDBM437269 2-((4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H- pyrazol-1-yl)methyl)benzonitrile::US10617680, Example 3::US11020380, Example 3

SMILES Cn1cc(ccc1=O)-c1cnn(Cc2ccccc2C#N)c1

InChI Key InChIKey=WEBQGNRWPQEGEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437269   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437269BDBM437269(2-((4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437269BDBM437269(2-((4-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent