BDBM437271 1-methyl-5-(1-(pyridin-2-ylmethyl)-1H-pyrazol-4-yl) pyridin-2(1H)-one::US10617680, Example 5::US11020380, Example 5

SMILES Cn1cc(ccc1=O)-c1cnn(Cc2ccccn2)c1

InChI Key InChIKey=FQKCUYYDGFHYRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437271   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437271BDBM437271(1-methyl-5-(1-(pyridin-2-ylmethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437271BDBM437271(1-methyl-5-(1-(pyridin-2-ylmethyl)-1H-pyrazol-4-yl...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent