BDBM437352 1-(5-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)-1-methyl-2-oxo- 1,2-dihydropyridin-4-yl)-1H-pyrrole-3-carboxylic acid::US10617680, Example 86::US11020380, Example 86

SMILES Cn1cc(-c2cnn(CC3CC3)c2)c(cc1=O)-n1ccc(c1)C(O)=O

InChI Key InChIKey=PBYGOIASWZDADD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437352   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437352BDBM437352(1-(5-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)-1-met...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437352BDBM437352(1-(5-(1-(cyclopropylmethyl)-1H-pyrazol-4-yl)-1-met...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent