BDBM437363 5-(1-(2-chlorophenyl)-1H-pyrazol-4-yl)-4-ethoxy-1- methylpyridin-2(1H)-one::US10617680, Example 97::US11020380, Example 281

SMILES CCOc1cc(=O)n(C)cc1-c1cnn(c1)-c1ccccc1Cl

InChI Key InChIKey=HZSKIEKQFZLAIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 437363   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437363BDBM437363(5-(1-(2-chlorophenyl)-1H-pyrazol-4-yl)-4-ethoxy-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437363BDBM437363(5-(1-(2-chlorophenyl)-1H-pyrazol-4-yl)-4-ethoxy-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437363BDBM437363(5-(1-(2-chlorophenyl)-1H-pyrazol-4-yl)-4-ethoxy-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent