BDBM437433 US10617680, Example 167::US11020380, Example 167::[5-(1-Benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2- dihydro-pyridin-4-yloxy]-acetonitrile

SMILES Cn1cc(-c2cnn(Cc3ccccc3)c2)c(OCC#N)cc1=O

InChI Key InChIKey=MKVRSIJHUXLOLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437433   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437433BDBM437433([5-(1-Benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2- ...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437433BDBM437433([5-(1-Benzyl-1H-pyrazol-4-yl)-1-methyl-2-oxo-1,2- ...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent