BDBM437453 N-[1-Benzyl-4-(4-ethoxy-1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl)-1H-pyrazol-3-yl]-acetamide::US10617680, Example 187::US11020380, Example 187

SMILES CCOc1cc(=O)n(C)cc1-c1cn(Cc2ccccc2)nc1NC(C)=O

InChI Key InChIKey=WXBLGXWHPGKQKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437453   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437453BDBM437453(N-[1-Benzyl-4-(4-ethoxy-1-methyl-6-oxo-1,6-dihydro...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437453BDBM437453(N-[1-Benzyl-4-(4-ethoxy-1-methyl-6-oxo-1,6-dihydro...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent