BDBM437461 5-(1-Benzyl-1H-pyrazol-4-yl)-1,6-dimethyl-1H-pyridin-2- one::US10617680, Example 195::US11020380, Example 195

SMILES Cc1c(ccc(=O)n1C)-c1cnn(Cc2ccccc2)c1

InChI Key InChIKey=YXAIAZBATBMHAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437461   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437461BDBM437461(5-(1-Benzyl-1H-pyrazol-4-yl)-1,6-dimethyl-1H-pyrid...)
Affinity DataIC50: 5.00E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437461BDBM437461(5-(1-Benzyl-1H-pyrazol-4-yl)-1,6-dimethyl-1H-pyrid...)
Affinity DataIC50: 5.00E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent