BDBM437476 2-[4-(5,1'-Dimethyl-6,6'-dioxo-1,6,1',6'-tetrahydro- [3,4']bipyridinyl-3'-yl)-pyrazol-1-yl]-benzonitrile::US10617680, Example 210::US11020380, Example 210

SMILES Cc1cc(-c2cc(=O)n(C)cc2-c2cnn(-c3ccccc3C#N)c2)c[nH]c1=O

InChI Key InChIKey=FOQKYANWDAMUPB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437476   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437476BDBM437476(2-[4-(5,1'-Dimethyl-6,6'-dioxo-1,6,1',6'-tetrahydr...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437476BDBM437476(2-[4-(5,1'-Dimethyl-6,6'-dioxo-1,6,1',6'-tetrahydr...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent