BDBM437495 2-{4-[4-(4-Methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydro- pyridin-3-yl]-pyrazol-1-yl}-benzoic acid::US10617680, Example 229

SMILES COc1ccc(cc1)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1ccccc1C(O)=O

InChI Key InChIKey=WVFWDRVBCHKBQZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437495   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437495BDBM437495(2-{4-[4-(4-Methoxy-phenyl)-1-methyl-6-oxo-1,6-dihy...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent