BDBM437512 2-{4-[1-Methyl-6-oxo-4-(3,4,5-trimethoxy-phenyl)-1,6- dihydro-pyridin-3-yl]-pyrazol-1-yl}-benzonitrile::US10617680, Example 246

SMILES COc1cc(cc(OC)c1OC)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1ccccc1C#N

InChI Key InChIKey=YWODHGFKSMOWBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437512   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437512BDBM437512(2-{4-[1-Methyl-6-oxo-4-(3,4,5-trimethoxy-phenyl)-1...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent