BDBM437523 2-[4-(5-Ethyl-1-methyl-6-oxo-1,6-dihydro-pyridin-3-yl)- pyrazol-1-yl]-benzoic acid::US10617680, Example 257::US11020380, Example 257

SMILES CCc1cc(cn(C)c1=O)-c1cnn(c1)-c1ccccc1C(O)=O

InChI Key InChIKey=YURVTQRJXIKOHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437523   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437523BDBM437523(2-[4-(5-Ethyl-1-methyl-6-oxo-1,6-dihydro-pyridin-3...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437523BDBM437523(2-[4-(5-Ethyl-1-methyl-6-oxo-1,6-dihydro-pyridin-3...)
Affinity DataIC50: 2.75E+3nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent