BDBM437570 N-[(dimethylamino)sulfonyl]-{2-[4-(4-cyclopropyl-1- methyl-6-oxo(3- hydropyridyl))pyrazolyl]phenyl}carboxamide::US10617680, Example 304::US11020380, Example 304

SMILES CN(C)S(=O)(=O)NC(=O)c1ccccc1-n1cc(cn1)-c1cn(C)c(=O)cc1C1CC1

InChI Key InChIKey=VGNVFFYVKWCJRI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437570   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437570BDBM437570(N-[(dimethylamino)sulfonyl]-{2-[4-(4-cyclopropyl-1...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437570BDBM437570(N-[(dimethylamino)sulfonyl]-{2-[4-(4-cyclopropyl-1...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent