BDBM437571 3-(4-(1,1'-dimethyl-2',6-dioxo-1,1',2',6-tetrahydro-[4,4'- bipyridin]-3-yl)-1H-pyrazol-1-yl)-4-methoxybenzonitrile::US10617680, Example 305::US11020380, Example 305

SMILES COc1ccc(cc1-n1cc(cn1)-c1cn(C)c(=O)cc1-c1ccn(C)c(=O)c1)C#N

InChI Key InChIKey=KGDPPUMCPBKLNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437571   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437571BDBM437571(3-(4-(1,1'-dimethyl-2',6-dioxo-1,1',2',6-tetrahydr...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437571BDBM437571(3-(4-(1,1'-dimethyl-2',6-dioxo-1,1',2',6-tetrahydr...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent