BDBM437603 2-chloro-6-(4-(1-methyl-4-(2-(4-methylpiperazin-1- yl)pyrimidin-5-yl)-6-oxo-1,6-dihydropyridin-3-yl)-1H- pyrazol-1-yl)benzonitrile::US10617680, Example 337::US11020380, Example 337

SMILES CN1CCN(CC1)c1ncc(cn1)-c1cc(=O)n(C)cc1-c1cnn(c1)-c1cccc(Cl)c1C#N

InChI Key InChIKey=NBQPWOJODLVTFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 437603   

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437603BDBM437603(2-chloro-6-(4-(1-methyl-4-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetCREB-binding protein(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 437603BDBM437603(2-chloro-6-(4-(1-methyl-4-(2-(4-methylpiperazin-1-...)
Affinity DataIC50: 500nMAssay Description:The CBP-inhibitory activity of the compounds described herein was determined by calculating the IC50. More specifically, CBP inhibitor activity was a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2020
Entry Details
US Patent