BDBM43762 1-(4-chloranyl-2-methyl-phenyl)-3-pyridin-2-yl-thiourea::1-(4-chloro-2-methyl-phenyl)-3-(2-pyridyl)thiourea::1-(4-chloro-2-methylphenyl)-3-(2-pyridinyl)thiourea::1-(4-chloro-2-methylphenyl)-3-pyridin-2-ylthiourea::MLS000575409::N-(4-chloro-2-methylphenyl)-N'-2-pyridinylthiourea::SMR000196643::cid_667573

SMILES C=CC(=O)N1CC(C)c2nn(-c3ccc(C4CC4)cc3O)c3c2C(C1)N(C(=O)c1cnc(C(F)(F)F)cc1N)CC3

InChI Key InChIKey=BMYHYBZRMXACAK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43762   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43762BDBM43762(1-(5-(4-amino-6- (trifluoromethyl) nicotinoyl)- 2-...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43762BDBM43762(1-(5-(4-amino-6- (trifluoromethyl) nicotinoyl)- 2-...)
Affinity DataIC50: 10nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent