BDBM43770 (3Z)-3-(2-oxidanylidene-2-thiophen-2-yl-ethylidene)-1,4-dihydroquinoxalin-2-one::(3Z)-3-(2-oxo-2-thiophen-2-ylethylidene)-1,4-dihydroquinoxalin-2-one::(3Z)-3-[2-keto-2-(2-thienyl)ethylidene]-1,4-dihydroquinoxalin-2-one::3-[2-oxo-2-(2-thienyl)ethylidene]-3,4-dihydro-2(1H)-quinoxalinone::MLS000705005::SMR000230609::cid_5410433

SMILES C=CC(=O)N1CC(OC2CC(C#N)C2)c2nn(-c3ccc(C4CCC4)cc3)c3c2C(C1)N(C(=O)c1cnc(C(F)(F)F)cc1N)CC3

InChI Key InChIKey=QTHQCKXCYPEECX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43770   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43770BDBM43770(3-((7-acryloyl-5-(4- amino-6- (trifluoromethyl) ni...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43770BDBM43770(3-((7-acryloyl-5-(4- amino-6- (trifluoromethyl) ni...)
Affinity DataIC50: 10nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent