BDBM43772 3-[(2-fluorobenzyl)thio]-6-(2-methoxyphenyl)pyridazine::3-[(2-fluorophenyl)methylsulfanyl]-6-(2-methoxyphenyl)pyridazine::3-[(2-fluorophenyl)methylthio]-6-(2-methoxyphenyl)pyridazine::MLS000678619::SMR000323857::cid_7206036

SMILES C=CC(=O)N1CCc2nn(-c3ccc(C4CC4)cc3O)c3c2C(C1)N(C(=O)c1cc(F)c(C(F)(F)F)nc1N)CC3

InChI Key InChIKey=WLNGNECPJIWIAF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43772   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43772BDBM43772(1-(5-(2-amino-5-fluoro- 6- (trifluoromethyl) nicot...)
Affinity DataIC50: 1.5nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [2-1432](Human)
MOMA Therapeutics, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 43772BDBM43772(1-(5-(2-amino-5-fluoro- 6- (trifluoromethyl) nicot...)
Affinity DataIC50: 35nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2026
Entry Details US Patent