BDBM437782 (2S)-3-(4- fluorophenyl)sulfonyl-N- [[6-[2- (trifluoromethyl)pyrimidin- 5-yl]pyrimidin-4-yl]methyl]- 3-azabicyclo[2.1.1]hexane- 2-carboxamide::US10597383, Example 1

SMILES Fc1ccc(cc1)S(=O)(=O)N1C2CC(C2)[C@H]1C(=O)NCc1cc(ncn1)-c1cnc(nc1)C(F)(F)F

InChI Key InChIKey=MATIEQPNROPBFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 437782   

LigandPNGBDBM437782((2S)-3-(4- fluorophenyl)sulfonyl-N- [[6-[2- (trifl...)
Affinity DataIC50: 42.9nMAssay Description:IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells expressing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2020
Entry Details
US Patent