BDBM443012 N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzothiazole-5-carboxamide::US10654814, Example 75

SMILES CC(C)c1ccc(cc1)-c1nc2cc(ccc2s1)C(=O)NO

InChI Key InChIKey=YIQVYQNMHZMEBO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 443012   

TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  13nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  900nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  28nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  500nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443012(N-hydroxy-2-[4-(1- methylethyl)phenyl]-1,3- benzot...)
Affinity DataIC50:  5.50E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent