BDBM443064 2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran-5- carboxamide::US10654814, Example 162

SMILES ONC(=O)c1ccc2oc(COc3cccc(F)c3)cc2c1

InChI Key InChIKey=RFGRVPIGCXCSIK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 443064   

TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  7nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  550nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 8(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  1.50E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  320nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  7nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM443064(2-[3-fluorophenoxy)methyl]-N- hydroxy-1-benzofuran...)
Affinity DataIC50:  3.50E+3nMAssay Description:The assay principle is well known and all necessary reagents like enzymes, substrates, developer and reference compounds are commercially available. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent