BDBM443319 6'-([1,1'-Biphenyl]-4-yl)-2'-oxo-1',4'- dihydro-2'H-spiro[pyrrolidine-3,3'- quinoline]-1-carbonitrile::US10654853, Example 92::US11236092, Example 92

SMILES O=C1Nc2ccc(cc2CC11CCN(C1)C#N)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NGRBLYJMHHFRMM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 443319   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443319BDBM443319(US10654853, Example 92 | 6'-([1,1'-Biphenyl]-4-yl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443319BDBM443319(US10654853, Example 92 | 6'-([1,1'-Biphenyl]-4-yl)...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent