BDBM443349 6'-(1-Methyl-6-oxo-1,6-dihydropyridin- 3-yl)-2'-oxo-1',4'-dihydro-2'H- spiro[pyrrolidine-3,3'-quinoline]-1- carbonitrile::US10654853, Example 122::US11236092, Example 122

SMILES Cn1cc(ccc1=O)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=FHAQTIUAPGEIQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 443349   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443349BDBM443349(US10654853, Example 122 | 6'-(1-Methyl-6-oxo-1,6-d...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443349BDBM443349(US10654853, Example 122 | 6'-(1-Methyl-6-oxo-1,6-d...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 443349BDBM443349(US10654853, Example 122 | 6'-(1-Methyl-6-oxo-1,6-d...)
Affinity DataIC50: 5.50E+3nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2022
Entry Details
US Patent