BDBM443357 3-(1-Cyano-2'-oxo-1',4'-dihydro-2'H- spiro[pyrrolidine-3,3'-quinolin]-6'-yl)- N,N-dimethylbenzamide::US10654853, Example 130

SMILES CN(C)C(=O)c1cccc(c1)-c1ccc(cc1)-c1ccc2NC(=O)C3(CCN(C3)C#N)Cc2c1

InChI Key InChIKey=GZWGPOBPWLYJDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 443357   

TargetOTU domain-containing protein 7B(Human)
Mission Therapeutics

US Patent
LigandPNGBDBM443357(US10654853, Example 130 | 3-(1-Cyano-2'-oxo-1',4'-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/1/2021
Entry Details
US Patent